Detail IJR (Indonesian Journal of Rheumatology) Informasi tentang Perhimpunan Reumatologi Indonesia

IJR Vol 9 No.2, July - December 2017; Neuropsychiatric Manifestation Screening among Systemic Lupus Erythematosus Patients in Hasan Sadikin General Hospital Bandung

Background: Systemic Lupus Erythematosus (SLE)
is an autoimmune diseases caused by deposition of
immune complex with the involvement of various organ
system and certain autoantibodies production. One of
the most significant manifestation is neuropsychiatric
symptoms, known as NPSLE (Neuropsychiatric Systemic
Lupus Erythematosus). This study aims to portray the
distribution of neuropsychiatric manifestation of SLE
patients using a screening method in Hasan Sadikin
General Hospital.
Method: An observative, descriptive categoric study,
with consecutive sampling were done. Data were
collected by spreading the questionnaire to subjects
diagnosed as SLE who visiting Hasan Sadikin General
Hospital during August-October 2016 and by tracing
their medical records. Data analyzed included age, sex,
education background, duration of lupus, diagnosis
criteria, ongoing therapy, and neuropsychiatric
Result: Samples volunteered in this study were 97
patients. Of them 94 patients (96.9%) were women and
47 patients (48.5%) were senior high school graduated.
Most common diagnosis criteria found was positive
ANA test (91.8%). Most necessary ongoing therapy
given was methylprednisolone (96.9%). Common
neuropsychiatric manifestations were mood disorders
(73,2%), headache (57,7%), and mononeuropathy
Conclusion: The common psychiatric, central nervous,
and peripheral nervous manifestations were mood
disorder, headache, and mononeuropathy, respectively.
Keywords: Neuropsychiatry, NPSLE Screening,
Systhemic Lupus Erythematosus.


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